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Marco Zaccaria: The Role of the Junctional Zone in the Management of Adenomyosis With Infertility
May 7, 2026, 12:08

Marco Zaccaria: The Role of the Junctional Zone in the Management of Adenomyosis With Infertility

Marco Zaccaria, Global Product Manager at ESGE European Society Gynecology Endoscopy, shared a post on LinkedIn:

“How important is it to identify and evaluate the endometrium-myometrium interface (JZ) via ultrasound in a women with adenomyosis?

On an ultrasound, the thickness of the junctionalzone (the inner layer of the myometrium, in direct contact with the endometrium) is considered normal when it measures between 5 and 8 mm

In diagnostic imaging for adenomyosis, a junctional zone (JZ) thickness of more than 12 mm is the most widely accepted indicator for a likely diagnosis

Look also for specific qualitative and quantitative markers:

JZ Ratio: A ratio of the maximum JZ thickness to the total myometrial thickness of >40% is often used as a diagnostic parameter

JZ Difference: A difference between the maximum and minimum thickness of the JZ (JZmax − JZmin) exceeding 5 mm

Morphological Changes: an irregular, ill-defined, or ‘hazy’ appearance of the junctional zone on ultrasound, often accompanied by small myometrial cysts or asymmetric thickening of the uterine walls

As clinical impact, increased JZ thickness is significantly linked to reproductive issues, including a higher risk of embryo implantation failure during IVF treatments

Enjoy reading and studying.”

Title: The role of the junctional zone in the management of adenomyosis with infertility

Authors: Sha Wang, Hua Duan

 

Marco Zaccaria: The Role of the Junctional Zone in the Management of Adenomyosis With Infertility

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