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Marco Zaccaria: Transvaginal Microwave Thermoablation for Uterine Fibroids
Marco Zaccaria/LinkedIn
Jun 25, 2026, 14:33

Marco Zaccaria: Transvaginal Microwave Thermoablation for Uterine Fibroids

Marco Zaccaria, Global Product Manager at ESGE European Society Gynecology Endoscopy, shared a post on LinkedIn:

“Now available! A fascinating video article on the interstitial myolysis procedure using microwave thermoablation via a transvaginal approach, published in the latest issue of the official ESGE – European Society for Gynaecological Endoscopy journal Facts Views and Vision

A 36-year-old multiparous woman with persistent abnormal uterine bleeding and pelvic pain related to a known uterine fibroid seeking a uterus-preserving treatment

Transvaginal ultrasound revealed a retroverted, enlarged uterus with a posterior type 2-5 fibroid measuring 45×37×49 mm (volume: 42.4 cm³)

Under conscious sedation, a 16G-27 cm microwave antenna was transvaginally
inserted and repositioned within the fibroid under continuous ultrasound guidance

Ablation was delivered in four
cycles at 20 W for a total duration of 194 seconds, with a cumulative net energy delivered of 3.3 kJ calculated by the device, while continuously assessing safety margins and tissue response

Immediate ultrasound evaluation showed a 42.7% volume reduction (from 42.4 to 24.3 cm³), loss of fibroid definition, and partial collapse, consistent with effective devascularisation

No complications occurred, and the patient was discharged the same day. At 4-month follow-up, fibroid volume reduction was sustained (41.7%), with complete symptom control under the previously ineffective hormonal therapy

Università degli Studi di Modena e Reggio Emilia

  • Prof. Antonio LA MARCA
  • Dr.ssa Maria Longo
  • Dr.ssa Sara Verra
  • Dr. Christian Battipaglia
  • Dr.ssa Nunzia Del Villano

You’ll find the link to the video article in the comments.”

Marco Zaccaria: Transvaginal Microwave Thermoablation for Uterine Fibroids

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ablation abnormal uterine bleeding Antonio La Marca Christian Battipaglia effective devascularisation ESGE - European Society for Gynaecological Endoscopy Fertility Fertility News fibroid definition Hormonal Therapy interstitial myolysis procedure Marco Zaccaria Maria Longo microwave thermoablation multiparous woman Nunzia Del Villano pelvic pain reproductive health Reproductive Medicine Sara Verra tissue response transvaginal approach transvaginal ultrasound uterus-preserving treatment
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