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Marco Zaccaria: Transvaginal Microwave Thermoablation for Uterine Fibroids
Jun 25, 2026, 14:33

Marco Zaccaria: Transvaginal Microwave Thermoablation for Uterine Fibroids

Marco Zaccaria, Global Product Manager at ESGE European Society Gynecology Endoscopy, shared a post on LinkedIn:

“Now available! A fascinating video article on the interstitial myolysis procedure using microwave thermoablation via a transvaginal approach, published in the latest issue of the official ESGE – European Society for Gynaecological Endoscopy journal Facts Views and Vision

A 36-year-old multiparous woman with persistent abnormal uterine bleeding and pelvic pain related to a known uterine fibroid seeking a uterus-preserving treatment

Transvaginal ultrasound revealed a retroverted, enlarged uterus with a posterior type 2-5 fibroid measuring 45×37×49 mm (volume: 42.4 cm³)

Under conscious sedation, a 16G-27 cm microwave antenna was transvaginally
inserted and repositioned within the fibroid under continuous ultrasound guidance

Ablation was delivered in four
cycles at 20 W for a total duration of 194 seconds, with a cumulative net energy delivered of 3.3 kJ calculated by the device, while continuously assessing safety margins and tissue response

Immediate ultrasound evaluation showed a 42.7% volume reduction (from 42.4 to 24.3 cm³), loss of fibroid definition, and partial collapse, consistent with effective devascularisation

No complications occurred, and the patient was discharged the same day. At 4-month follow-up, fibroid volume reduction was sustained (41.7%), with complete symptom control under the previously ineffective hormonal therapy

Università degli Studi di Modena e Reggio Emilia

  • Prof. Antonio LA MARCA
  • Dr.ssa Maria Longo
  • Dr.ssa Sara Verra
  • Dr. Christian Battipaglia
  • Dr.ssa Nunzia Del Villano

You’ll find the link to the video article in the comments.”

Marco Zaccaria: Transvaginal Microwave Thermoablation for Uterine Fibroids

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