Peter Humaidan: Impact of Sperm DNA Integrity on Embryo Quality and Live Birth in IVF
Peter Humaidan, Clinical Director at pMorph Ltd, shared a post on LinkedIn about a paper published in Andrology:
“In this new multi-centre study we again highlight the biological relevance of sperm DNA integrity for IVF reproductive outcomes. Importantly, we report that higher levels of double-stranded sperm DNA fragmentation, measured using the neutral Comet assay, are associated with poorer IVF success rates, including lower embryo quality and lower live birth rates. The findings suggest that assessing double-strand DNA damage could improve male fertility evaluation and help guide a more personalised treatment strategy in ART.”
Title: Double-stranded sperm DNA fragmentation measured with neutral comet assay as a predictor of IVF outcomes: evidence from three European clinics in a multi-centred prospective study
Authors: Peter Humaidan , Betina B Povlsen, Andrew J Drakeley, Mette B Jensen, Anette V Gabrielsen, Sara H McDowell, Luca Moore, Craig J Ledgerwood, Lewis Rae, Alastair Sloan, Martin Lawlor, Lynsey Poots, Elizabeth Bailie, Rebecca L Lunt, Emily Newton, Rachel C Gregoire, Tara C B Moore, Sandro C Esteves
Read the full article.
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Apr 10, 2026, 16:06Madhur Hamine: IVF Does not Have a Technology Problem It Has an Access Problem
-
Apr 10, 2026, 15:00Jane Fisher: Antenatal Screening and Diagnosis – Where are We Now and Where are We Going?
-
Apr 10, 2026, 14:54Post-Warming Re-Expansion and Contraction Dynamics of Vitrified Blastocysts – Fertility and Sterility
-
Apr 10, 2026, 14:37Apply Now for Vacation Scholarship on Summer Research Project – SRF
-
Apr 10, 2026, 14:33AJOG-MFM Launches New Podcast Series on Love, Science, and Human Connection
-
Apr 10, 2026, 14:26Christopher Robinson: Doppler Ratios for Evaluating Placental Function Near Term
-
Apr 10, 2026, 14:23ART Tied to Increased Risk of Endometriosis in Offspring – Fertility and Sterility
-
Apr 10, 2026, 14:15Christopher Barratt’s Lecture on Human Sperm’s Phenotypic Screening – SRF
-
Apr 10, 2026, 13:12President’s Achievement Awards in Women’s Health Research – SRI