Fereshteh Safian: A Case From the IVF Lab On Dysmorphic Oocytes and Embryo Development
Fereshteh Safian, Clinical Embryologist at Pooyesh Fertility Center, shared a post on LinkedIn:
“In this cycle, we observed a 25-year-old patient with highly dysmorphic oocytes showing pronounced cytoplasmic abnormalities across multiple retrieved oocytes, making the assessment of maturity particularly challenging.
Interestingly, a similar oocyte morphology had been documented in a previous cycle which ultimately resulted in a successful live birth.
In the current cycle, 6 oocytes underwent ICSI, resulting in 5 cleavage-stage embryos. Two embryos were vitrified on day 3, while the remaining three continued developments and reached the early blastocyst stage on day 5, showing persistence of the same morphological pattern, when they were vitrified.
The recurrence of this distinctive oocyte morphology across different cycles suggests a persistent phenotype rather than an isolated observation.
The underlying mechanism remains unclear. Similar observations from other IVF laboratories would be interesting to compare.”
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Oct 19, 2026, 17:08Shweta Mendiratta: A Baby Boy Was Born From an Embryo that Had Been Frozen for More Than 31 Years
-
Oct 19, 2026, 17:06Partha Sarathi Das: Fertility Begins Before Birth – The Role of Developmental Biology, Genetics, and Epigenetics
-
Oct 19, 2026, 17:04Khalil Faaed: What Morphological Abnormalities Reveal About Oocyte Competence in IVF
-
Oct 19, 2026, 17:01Daniel Plaksin: HLA-G Glycosylation Emerges as a Potential Mechanism in RPL
-
Oct 19, 2026, 16:59Justin Houman: 4 Checks Before Anyone Starts Testosterone
-
Oct 19, 2026, 16:57Sonia Khourta: Proud to Be Part of the ART Fertility Family
-
Oct 19, 2026, 16:55ACOG Is Moving the Needle on Menopause
-
Oct 19, 2026, 16:53Gila Zarbiv: Why Isn’t Continuity of Midwife Care Happening Everywhere?
-
Oct 19, 2026, 16:50Laura Eyeh Anwah: Why Pregnant Women Should Attend 8 Antenatal Visits Instead of 4