Fereshteh Safian: A Case From the IVF Lab On Dysmorphic Oocytes and Embryo Development
Fereshteh Safian, Clinical Embryologist at Pooyesh Fertility Center, shared a post on LinkedIn:
“In this cycle, we observed a 25-year-old patient with highly dysmorphic oocytes showing pronounced cytoplasmic abnormalities across multiple retrieved oocytes, making the assessment of maturity particularly challenging.
Interestingly, a similar oocyte morphology had been documented in a previous cycle which ultimately resulted in a successful live birth.
In the current cycle, 6 oocytes underwent ICSI, resulting in 5 cleavage-stage embryos. Two embryos were vitrified on day 3, while the remaining three continued developments and reached the early blastocyst stage on day 5, showing persistence of the same morphological pattern, when they were vitrified.
The recurrence of this distinctive oocyte morphology across different cycles suggests a persistent phenotype rather than an isolated observation.
The underlying mechanism remains unclear. Similar observations from other IVF laboratories would be interesting to compare.”
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Jun 21, 2026, 15:27Ernesto Figueiro-Filho: Honoured to Receive the SOGC Regional Achievement Award at ACSC 2026
-
Jun 21, 2026, 14:54Meet Divya Kelath Shah in Our Latest Member Spotlight – ASRM
-
Jun 21, 2026, 14:48Mastering Interventional Ultrasound with Francesco D’Antonio – ISUOG
-
Jun 21, 2026, 14:38Asma Khalil: Clinical Obstetrics and Gynaecology Achieves Strong 2025 Citation Metrics
-
Jun 21, 2026, 14:36Diana Kayal: What Every IVF Patient Should Know About Twin Pregnancies
-
Jun 21, 2026, 14:23The 2026 National Trainees Conference Officially Begins – RCOG
-
Jun 21, 2026, 14:10Christopher Robinson: Substance Use and Use Disorders During Pregnancy and the Postpartum Period
-
Jun 21, 2026, 13:48FIGO – WHO Webinar on Updated Medical Eligibility Criteria – IJGO
-
Jun 21, 2026, 13:40Webinar On Abdominal Repair of High Vaginal Tears with Haemodynamic Compromise – GEFOG Health Foundation