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Biochemical Pregnancies Affect Up to 31% of IVF Cycles – Fertility Plus

Fertility Plus/LinkedIn

Jul 2, 2026, 11:34

Biochemical Pregnancies Affect Up to 31% of IVF Cycles – Fertility Plus

Fertility Plus shared a post on LinkedIn:

“The IVF Loss No One Talks About – But Affects Up to 31% of Cycles – Biochemical pregnancy

She saw the positive pregnancy test at 6am. A week later, there was nothing on the scan. Many call it a ‘chemical pregnancy’ or say ‘at least you can get pregnant.’ But for her, it felt like a real loss – and she wanted real answers.

Biochemical pregnancies are surprisingly common in IVF, affecting up to 31% of cycles. Even with chromosomally normal embryos, the rate stays high at 18.3%. This often points to issues with the endometrium, progesterone levels, or lining thickness – not the embryo itself.

The hopeful news? Women who experience a biochemical pregnancy have a 38.4% chance of ongoing clinical pregnancy in their next IVF cycle – higher than the 27.3% for those with a completely negative result. It shows implantation started, and that matters.

You deserve proper investigation and support after this kind of loss. It’s not just bad luck – it’s information that can guide better care next time.

If you’re navigating IVF losses or want honest guidance, subscribe and follow for more compassionate, evidence-based insights to support your path forward!

Reference: Ortiz N et al. Reprod Biomed Online. 2024. PMC11308629. | Bates GW et al. cited in Xiao Z ‘Biochemical Pregnancy During Assisted Conception.’

For any inquiries or questions.”

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