Peter Humaidan: Impact of Sperm DNA Integrity on Embryo Quality and Live Birth in IVF
Peter Humaidan, Clinical Director at pMorph Ltd, shared a post on LinkedIn about a paper published in Andrology:
“In this new multi-centre study we again highlight the biological relevance of sperm DNA integrity for IVF reproductive outcomes. Importantly, we report that higher levels of double-stranded sperm DNA fragmentation, measured using the neutral Comet assay, are associated with poorer IVF success rates, including lower embryo quality and lower live birth rates. The findings suggest that assessing double-strand DNA damage could improve male fertility evaluation and help guide a more personalised treatment strategy in ART.”
Title: Double-stranded sperm DNA fragmentation measured with neutral comet assay as a predictor of IVF outcomes: evidence from three European clinics in a multi-centred prospective study
Authors: Peter Humaidan , Betina B Povlsen, Andrew J Drakeley, Mette B Jensen, Anette V Gabrielsen, Sara H McDowell, Luca Moore, Craig J Ledgerwood, Lewis Rae, Alastair Sloan, Martin Lawlor, Lynsey Poots, Elizabeth Bailie, Rebecca L Lunt, Emily Newton, Rachel C Gregoire, Tara C B Moore, Sandro C Esteves
Read the full article.
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Apr 1, 2026, 13:32Pregnancy Loss Leave and Recognition in Ireland! – PLRG
-
Apr 1, 2026, 13:19Christopher Robinson: Immune Tolerance Breakdown In Pregnancy!
-
Apr 1, 2026, 13:14How Many Cells Are Enough in Blastocyst Biopsy? – Fertility Plus
-
Apr 1, 2026, 13:09Follicular Fluid PFAS May Influence IVF Outcomes – Fertility and Sterility
-
Apr 1, 2026, 12:48Taarika Ramesh: Rethinking IVF Stimulation With Progestin-Primed Protocols
-
Apr 1, 2026, 12:41Shivam Jha: What is the Importance of Ultrasound During Pregnancy?
-
Apr 1, 2026, 12:18Abnormal Spermogram Is Not an Explanation, It Is a Starting Point – Cesar Fertility
-
Apr 1, 2026, 11:41Christopher Robinson: Racial Disparities in Postoperative Benign Hysterectomy Outcomes
-
Apr 1, 2026, 11:26Sergei Gorlovetsky: Most Fertility Clinics Are Losing Patients Between Interested and Started Treatment