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Nathalie Massin: 73% of Fresh IVF Cycles are Actually ICSI
Nathalie Massin/LinkedIn
May 17, 2026, 07:28

Nathalie Massin: 73% of Fresh IVF Cycles are Actually ICSI

Nathalie Massi, President of Fertility Check Up Association, shared a post on LinkedIn:

“73% of fresh IVF cycles are actually ICSI.

And a large part without clear male indication.

Europe figure 2021, ESHRE EIM report 2024. (Nothing has changed since.)

ICSI has profoundly changed the management of male infertility. Without it, many couples would never have had access to pregnancy. The debate is not about ICSI. He is on systematic ICSI.

In an interview, I see the same sentence come back: ‘I was given an ICSI, I never really understood why…’»

The subject is rarely asked. However, three recent pieces of evidence converge: the randomized trial Wang et al. (Lancet 2024, 2,387 couples), the INVICSI trial (Nature Medicine 2025), and a 2024 meta-analysis on nearly a million cycles say the same thing.

  • In couples without a male factor, ICSI does not give more live births than conventional IVF.
  • The meta-analysis even leans in favor of IVF.

This carousel is a call to ask the question again, file by file. What are we afraid of?

If the semen analysis is normal, ask yourself why ICSI is chosen?.”

Nathalie Massin: 73% of Fresh IVF Cycles are Actually ICSI

Stay updated on all scientific advances in the field of fertility with Fertility News.

Europe figure 2021 Fertility Fertility News ICSI INVICSI trial IVF IVF Cycles male factor male indication male infertility million cycles Nature Medicine 2025 Pr Nathalie Massin pregnancy reproductive health Reproductive Medicine semen analysis systematic ICSI
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