Marieke Ogay։ Antioxidant Status and Magnesium։ Key to Miscarriage Risk?
Marieke Ogay, Bachelor in Midwifery (Bachelier Sage-Femme) at Erasmushogeschool Brussel, shared a post on LinkedIn:
“A prospective study of 95 pregnant women (35 with ≥3 previous miscarriages, 60 controls) found clear biochemical differences already between 11–14 weeks of pregnancy. Women with recurrent miscarriage histories had:
Higher antioxidant enzyme activity (SOD‑1 and GSH‑Px), suggesting a mobilised but strained defense against oxidative stress.
Lower total antioxidant status (TAS) and lower serum magnesium levels, pointing to an exhausted antioxidant system and possible role for magnesium as a predictive marker. Higher beta‑hCG values, while PAPP‑A did not significantly differ between groups.
The authors propose that a pattern of higher SOD‑1 and GSH‑Px, with lower TAS and magnesium, could help identify women at increased risk of spontaneous miscarriage, and argue for closer follow‑up and consideration of antioxidant and magnesium support later in pregnancy. For clinicians and researchers, this reinforces the need to look beyond anatomy, genetics and hormones, and to integrate oxidative‑stress and micronutrient assessment into recurrent miscarriage work‑ups.
Source: Bogavac M et al. ‘Biomarkers of oxidative stress in pregnant women with recurrent miscarriages.’ J Lab Med, 2019.”
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Apr 30, 2026, 18:45AI in Ultrasound Follicular Monitoring Moves Toward Clinical Decision Support – RBMO
-
Apr 30, 2026, 11:42ASRM Encourages Registration for Conference on Practice Growth and Innovation
-
Apr 30, 2026, 11:26ESHRE and ALPHA Launch Global Survey to Update ART Laboratory KPIs
-
Apr 30, 2026, 11:10Susanne Johnson: Advanced Gynaecology Ultrasound Course Day 2
-
Apr 30, 2026, 11:02Platelets Reduce Oxidative Stress Damage in Human Endometrial Stromal Cells in Vitro – RBMO
-
Apr 30, 2026, 10:57GREEG Day 2026: Elevate Your Ultrasound Expertise – GREEG
-
Apr 30, 2026, 10:49Up to Two-Thirds of Elite Female Athletes Experience Irregular Periods – Fertility Plus
-
Apr 30, 2026, 10:47Applications for the ESHRE5 Young Ambassadors 2026 are Still OPEN, But Not for Long! – ESHRE
-
Apr 30, 2026, 10:42The Link Between Lifestyle and Anti-Müllerian Hormone – RBMO