Platelets Reduce Oxidative Stress Damage in Human Endometrial Stromal Cells in Vitro – RBMO
Reproductive BioMedicine Online (RBMO) shared a post on LinkedIn:
“This new study into human endometrial stromal cell damage, published in the Experimental Reproductive Biology section of our June issue, shows that platelet concentrates can alleviate oxidative damage in T-HESC in vitro by reducing ROS accumulation, improving inflammatory balance, and reducing the Bax/Bcl-2 ratio.
Importantly, the authors found that activation of the PI3K/AKT signalling pathway can mediate this protective effect, representing a potential mechanism underlying the therapeutic benefits of platelet concentrates in treating endometrial injury and ameliorating thin endometrium.
The full paper is available to RBMO subscribers now, ahead of press, from issue 52.6.”
Title: Platelets reduce oxidative stress damage in human endometrial stromal cells in vitro
Authors: Yixuan Zhu, Zhengyu Song, Bingbing Liu, Aifang Gao, Fangli Tian, Haiqing Tian
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