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Sonal Pendharkar Kulkarni: When the Vaginal Microbiome Is Off, Everything Is Affected!
Sonal Pendharkar Kulkarni/LinkedIn
Dec 14, 2025, 08:29

Sonal Pendharkar Kulkarni: When the Vaginal Microbiome Is Off, Everything Is Affected!

Sonal Pendharkar Kulkarni, CSO and Co-founder of Uvisa Health, shared a post on LinkedIn about a paper by Axel Skafte-Holm et al. published in The Lacnet:

“The science is ctching up to what many women already feel: When the vaginal microbiome is off, everything is affected!

A fascinating new Danish collaborative research by Axel Skafte-Holm and Jørgen Skov Jensen at Statens Serum Institut tracked nearly 2,000 pregnant women and the findings really resonated with my initial understanding of the vaginal microbiome and it’s far-reaching impact on women’s health, including pregnancy:

Lactobacillus crispatus rich vaginal microbiome was more associated with healthy pregnancies
Ureaplasma spp and Mycoplasma hominis were not associated with loss, an important nuance!
Vaginal dysbiosis, i.e. a mixed and diverse vaginal microbiome was significantly associated with pregnancy loss

What stood out most?

  • It’s the overall stability and balance of the microbiome that matters the most.
  • A stable microbiome sets the trajectory for what happens next.

This is exactly why at UVISA Health , we’re focused on creating solutions that support women’s natural microbial balance and not disrupt it.

Congratulation to all the authors…great work.”

Title: The role of the vaginal microbiota, sexually transmitted infections, ureaplasmas, and Mycoplasma hominis in pregnancy loss: a prospective study in pregnant women in Denmark

Authors: Axel Skafte-Holm, Thomas Roland Pedersen, Anna Sandager, Rikke Damkjær Maimburg, Camilla Lindahl, Anja Vad Søndergaard, Kirsten Salado-Rasmussen, Anna Cäcilia Ingham, Niels Uldbjerg, Jørgen Skov Jensen

Read the full article.

Sonal Pendharkar Kulkarni: When the Vaginal Microbiome Is Off, Everything Is Affected!

Stay updated on all scientific advances in the field of fertility with Fertility News.

Fertility Fertility News Headlines Lactobacillus crispatus Mycoplasma hominis reproductive health Reproductive Medicine Sonal Pendharkar Kulkarni Ureaplasma spp Vaginal dysbiosis vaginal microbiome
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