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Clinical Study Supports Continued IVF After Unsuccessful First Transfer – RBMO
RBMO
Apr 17, 2026, 03:05

Clinical Study Supports Continued IVF After Unsuccessful First Transfer – RBMO

Reproductive BioMedicine Online (RBMO) shared a post on LinkedIn about a paper by Francesca Barretta et al. published in RBMO:

“This study found no significant increase in the odds of pregnancy loss in a second frozen embryo transfer (FET) among patients who experienced either a clinical- or biochemical pregnancy loss (CPL/BPL) in their first FET, regardless of whether the embryo was euploid or untested.

Similarly, the authors report no significant difference in live birth rates following a second FET after an adverse pregnancy outcome in the first FET.

Their findings provide reassurance that a failed first FET does not increase the odds of recurrence in a subsequent transfer – information crucial for counselling patients and supporting their decision-making as they continue ART treatments after an initial pregnancy loss.

The full paper is available now as a pre-proof to RBMO subscribers from our April issue, now.”

Title: Biochemical or clinical pregnancy loss after first embryo transfer does not affect subsequent transfer outcome

Authors: Francesca Barretta, Erkan Kalafat, Blake Vessa, Cheri Margolis, Christine Whitehead, Marie Werner, Baris Atac, Emre Seli

RBMO

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Baris Atac biochemical pregnancy loss Blake Vessa BPL Cheri Margolis Christine Whitehead CPL Emre Seli Erkan Kalafat Fertility Fertility News FET Francesca Barretta frozen embryo transfer Marie Werner RBMO Reproductive BioMedicine Online reproductive health Reproductive Medicine
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