The Egg’s Engine Is Fed Plenty of Fuel, It Just Can’t Burn It – Fertility Plus
Fertility Plus shared a poat on LinkedIn:
“The egg’s engine is fed plenty of fuel. It just can’t burn it.
Did you know that the aging of an egg isn’t about a lack of fuel, but rather an inefficient engine?
Recent research reveals that as eggs age, they receive plenty of glucose and pyruvate, but their main energy-producing pathway—the TCA cycle—becomes blocked. This leads to a buildup of fuel that isn’t utilized effectively, causing a drop in key energy molecules and antioxidant balance.
The surrounding cells may even kick into high gear to help, but the challenge remains: it’s not a shortage of resources, but an engine that can’t keep up!
Let’s dive deeper into this fascinating study by Smits et al. (2023). Understanding the intricacies of egg aging could revolutionize reproductive health!”

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