Insights on Molecular Heterogeneity in Endometriosis Treatment – HER Heard
HER Heard shared a post by Femtech Insider on LinkedIn:
“Important breakthrough in our understanding of Endometriosis: ‘Endometriosis is currently classified based on symptoms and anatomical or surgical features, but these approaches don’t capture the biological programs active inside the tissue. Our work shows that what looks like unpredictable variability between patients actually reflects recurring cellular states that shape how the disease behaves and responds to treatment. This creates an opportunity to move toward more biologically informed patient stratification in research and clinical trials.'”
Quoting Femtech Insider’s post, adding:
“France-based biotech endogene.bio has published research suggesting that endometriosis is molecularly heterogeneous across patients, lesion sites, and cell types – a finding that could help explain why patients often experience different outcomes with the same therapy.
The preprint, titled ‘Beyond one-size-fits-all: single-cell transcriptomic signatures predict drug efficacy and reveal responder subgroups in endometriosis,’ combines single-cell RNA sequencing with a computational drug-response framework to identify distinct cellular response patterns that may predict which therapies are most likely to work for specific patient groups.
‘Endometriosis is currently classified based on symptoms and anatomical or surgical features, but these approaches don’t capture the biological programs active inside the tissue. Our work shows that what looks like unpredictable variability between patients actually reflects recurring cellular states that shape how the disease behaves and responds to treatment. This creates an opportunity to move toward more biologically informed patient stratification in research and clinical trials.’ Cristina Fernández Molina, Co-founder and Head of Science at endogene.bio
Full story.”
Stay updated on all scientific advances in the field of fertility with Fertility News.
-
Jun 15, 2026, 12:21Zara Grigoryan: Open Expert Dialogue to Shape Women’s Health in Armenia
-
Jun 15, 2026, 12:12Abhishek Saxena։ Can a 5PN Embryo Develop Normally?
-
Jun 15, 2026, 12:02Does Growth Hormone Help in IVF? – Fertility Plus
-
Jun 15, 2026, 11:55Allen Morgan: PRP in Fertility Treatment, Emerging Evidence and Future Directions
-
Jun 15, 2026, 11:49Hereditary Gynecologic Cancer Care Is Evolving, but Access and Health Systems Remain Unequal – IJGO
-
Jun 15, 2026, 11:41Celebrating Community and Support at the Annual Fertili’Tea Party! – CFAS
-
Jun 15, 2026, 11:37Christopher Robinson: Outcomes in Late Preterm and Term Births with Gestational Diabetes vs Normoglycemia
-
Jun 15, 2026, 11:34Registration Now Open for Fertility 2027 – British Fertility Society
-
Jun 15, 2026, 11:28Ioakeim Sapantzoglou: Excited to Share Our Latest Publication in Archives of Gynecology and Obstetrics!